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Middle East Respiratory Syndrome Coronavirus Nucleoprotein (MERS-CoV NP) Antibody
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Catalogue No: abx201381
Price:
US$362.50
(Size: 100 µl)
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Middle East Respiratory Syndrome Coronavirus Nucleoprotein (MERS-CoV NP) Antibody is a Rabbit Polyclonal antibody for the detection of Middle East Respiratory Syndrome Coronavirus Nucleoprotein (MERS-CoV NP). Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Research Articles on Middle East Respiratory Syndrome Coronavirus Nucleoprotein (MERS-CoV NP)
| Target | Middle East Respiratory Syndrome Coronavirus Nucleoprotein (MERS-CoV NP) |
| Clonality | Polyclonal |
| Reactivity | Virus |
| Tested Applications | ELISA |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant MERS-CoV Nucleoprotein / NP protein |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by Protein A affinity chromatography. 0.2 µm filtered. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |