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Mitogen-Activated Protein Kinase 14 (MAPK14) Antibody
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Catalogue No: abx216706
Price:
US$406.00
(Size: 100 µg)
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Mitogen Activated Protein Kinase 14 (MAPK14) Antibody is a Rabbit Polyclonal antibody for the detection of p38. Mitogen Activated Protein Kinase 14 (MAPK14), also known as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38 alpha, and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T (H) 17 differentiation and inflammation. It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell. This protein has 4 isoforms produced by alternative splicing.
Research Articles on Mitogen-Activated Protein Kinase 14 (MAPK14)
| Target | Mitogen-Activated Protein Kinase 14 (MAPK14) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | mitogen-activated protein kinase 14 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q16539 (UniProt, ExPASy) |
| UniProt Entry Name | MK14_HUMAN |
| Gene Symbol | MAPK14 |
| GeneID | 1432 |
| OMIM | 600289 |
| HGNC | 6876 |
| KEGG | hsa:1432 |
| Ensembl | ENSG00000112062 |
| String | 9606.ENSP00000229795 |
| Molecular Weight | Observed MW: 30-41 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |