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MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 (MKNK1) Antibody
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Catalogue No: abx033204
Price:
US$326.25
(Size: 80 µl)
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MKNK1 encodes a predicted 424-amino acid protein containing a sequence typical of the catalytic domain of serine/threonine kinases and a putative N-terminal nuclear localization signal sequence.C-terminal region of MKNK1 was phosphorylated and activated in vivo and in vitro by ERK1 and p38 MAP kinases, but not by JNK/SAPK. The activated ERK is essential for the activation of MKNK1 in insect cells. MKNK1 was activated following stimulation of HeLa cells with a variety of extracellular stimuli. MNK1 bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2, and also binds strongly to the stress-activated kinase, p38.
Research Articles on MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 (MKNK1)
| Target | MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 (MKNK1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MKNK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BUB5 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQ20, D3DQ21, O00312, Q5TC06, Q5TC07, Q6V0N6 |
| UniProt Entry Name | MKNK1_HUMAN |
| String | 9606.ENSP00000361014 |
| Molecular Weight | Calculated MW: 51.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse MKNK1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |