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Mixed Lineage Kinase 2 (MLK2) Antibody
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Catalogue No: abx033764
Price:
US$290.00
(Size: 80 µl)
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MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Research Articles on Mixed Lineage Kinase 2 (MLK2)
| Target | Mixed Lineage Kinase 2 (MLK2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 628-659 amino acids from the C-terminal region of human MLK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02779 (UniProt, ExPASy) |
| UniProt Secondary AC | Q12761, Q14871 |
| UniProt Entry Name | M3K10_HUMAN |
| NCBI Accession | NP_002437.2 |
| KEGG | hsa:4294 |
| String | 9606.ENSP00000253055 |
| Molecular Weight | Calculated MW: 104 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |