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Mixed Lineage Kinase-Related Kinase (MLKLAK) Antibody
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Catalogue No: abx033850
Price:
US$290.00
(Size: 80 µl)
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MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
Research Articles on Mixed Lineage Kinase-Related Kinase (MLKLAK)
| Target | Mixed Lineage Kinase-Related Kinase (MLKLAK) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 271-300 amino acids from the Central region of human MLKLAK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NYL2 (UniProt, ExPASy) |
| UniProt Entry Name | M3K20_HUMAN |
| String | 9606.ENSP00000364361 |
| Molecular Weight | Calculated MW: 91.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse MAP3K20. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |