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Matrix Metalloproteinase 13 (MMP13) Antibody
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Catalogue No: abx027550
Price:
US$326.25
(Size: 80 µl)
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Research Articles on Matrix Metalloproteinase 13 (MMP13)
| Target | Matrix Metalloproteinase 13 (MMP13) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 253-282 amino acids from the Central region of human MMP13. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P45452 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K846, B2RCZ3, Q6NWN6 |
| UniProt Entry Name | MMP13_HUMAN |
| KEGG | hsa:4322 |
| String | 9606.ENSP00000260302 |
| Molecular Weight | Calculated MW: 53.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Horse MMP13. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |