+44 (0) 1223 755950
+1 832 327 7413
Matrix Metalloproteinase 2 (MMP2) Antibody
REQUEST MORE INFO
Catalogue No: abx004769
Price:
US$348.00
(Size: 60 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
MMP2 Antibody is a Rabbit Polyclonal antibody against MMP2. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Matrix Metalloproteinase 2 (MMP2)
| Target | Matrix Metalloproteinase 2 (MMP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human MMP2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P08253 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6U1, B4DWH3, E9PE45, Q9UCJ8 |
| UniProt Entry Name | MMP2_HUMAN |
| Gene Symbol | MMP2 |
| GeneID | 4313 |
| NCBI Accession | NP_004521.1 |
| KEGG | hsa:4313 |
| String | 9606.ENSP00000219070 |
| Molecular Weight | Calculated MW: 65 kDa/68 kDa/73 kDa Observed MW: 73 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |