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Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3) Antibody
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Catalogue No: abx027449
Price:
US$326.25
(Size: 80 µl)
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Research Articles on Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3)
| Target | Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human MMP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P08254 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R8B8, Q3B7S0, Q6GRF8 |
| UniProt Entry Name | MMP3_HUMAN |
| KEGG | hsa:4314 |
| String | 9606.ENSP00000299855 |
| Enzyme Commission Number | EC 3.4.24.17 EC 3.4.24 |
| Molecular Weight | Calculated MW: 54 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |