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Matrix Metalloproteinase 8 (MMP8) Antibody
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Catalogue No: abx027560
Price:
US$326.25
(Size: 80 µl)
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Research Articles on Matrix Metalloproteinase 8 (MMP8)
| Target | Matrix Metalloproteinase 8 (MMP8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMP8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P22894 (UniProt, ExPASy) |
| UniProt Secondary AC | Q45F99 |
| UniProt Entry Name | MMP8_HUMAN |
| Gene Symbol | MMP8 |
| KEGG | hsa:4317 |
| String | 9606.ENSP00000236826 |
| Enzyme Commission Number | EC 3.4.24.34 EC 3.4.24 |
| Molecular Weight | Calculated MW: 53.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |