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Matrix Metalloproteinase-9 (MMP9) Antibody
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Catalogue No: abx011408
Price:
US$420.50
(Size: 100 µl)
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Research Articles on Matrix Metalloproteinase-9 (MMP9)
| Target | Matrix Metalloproteinase-9 (MMP9) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MMP9 expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14780 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7V9, Q3LR70, Q8N725, Q9H4Z1, Q9UCJ9, Q9UCL1, Q9UDK2 |
| UniProt Entry Name | MMP9_HUMAN |
| Gene Symbol | MMP9 |
| GeneID | 4318 |
| OMIM | 120361 |
| HGNC | 7176 |
| KEGG | hsa:4318 |
| Ensembl | ENSG00000100985 |
| String | 9606.ENSP00000361405 |
| Enzyme Commission Number | EC 3.4.24 EC 3.4.24.35 |
| Molecular Weight | 92 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |