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Matrix Metalloproteinase-9 (MMP9) Antibody
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Catalogue No: abx032734
Price:
US$290.00
(Size: 80 µl)
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Research Articles on Matrix Metalloproteinase-9 (MMP9)
| Target | Matrix Metalloproteinase-9 (MMP9) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 644-673 amino acids from the C-terminal region of human MMP9. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14780 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7V9, Q3LR70, Q8N725, Q9H4Z1, Q9UCJ9, Q9UCL1, Q9UDK2 |
| UniProt Entry Name | MMP9_HUMAN |
| NCBI Accession | NP_004985.2 |
| KEGG | hsa:4318 |
| String | 9606.ENSP00000361405 |
| Enzyme Commission Number | EC 3.4.24 EC 3.4.24.35 |
| Molecular Weight | Calculated MW: 78.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |