Monocyte Chemotactic Protein-2 (CCL8) Protein

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Catalogue No: abx260336
Price: US$261.00
(Size: 2 µg)

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Datasheet SDS
Human Monocyte Chemotactic Protein-2 (CCL8) Protein is a recombinant chemokine.

Target MCP 2
Origin Human
Expression Recombinant
Tested Applications SDS-PAGE
Host E. coli
Conjugation Unconjugated
Form Lyophilized
Purity > 95% (SDS-PAGE and RP-HPLC)
Reconstitution It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-2in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage MCP2 should be stored desiccated below -18 °C. Upon reconstitution CCL8 should be stored at 4 °C between 2-7 days and for future use below -18 °C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P80075 (UniProt, ExPASy)
UniProt Secondary AC A0AV77, P78388
UniProt Entry Name CCL8_HUMAN
KEGG hsa:6355
String 9606.ENSP00000378118
Sequence The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Asp-Ser-Val.
Biological Activity The biological activity was determined by measuring the dose dependent mobilization of intracellular calcium (calcium flux) with human THP-1 cells. Significant calcium mobilization is observed with 5ng/mL of recombinant human MCP-2. Human MCP-2 also induces dose dependent chemotaxis of human THP-1 cells with an ED5=3-1 ng/mL  corresponding to a Specific Activity of 1,-33,334IU/mg.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

Not for human consumption, cosmetic, therapeutic or diagnostic use.
Research Articles on MCP 2


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