+44 (0) 1223 755950
+1 832 327 7413
Click on the image to see the image legend
Target | MCP 2 |
Origin | Human |
Expression | Recombinant |
Tested Applications | SDS-PAGE |
Host | E. coli |
Conjugation | Unconjugated |
Form | Lyophilized |
Purity | > 95% (SDS-PAGE and RP-HPLC) |
Reconstitution | It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-2in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
Storage | MCP2 should be stored desiccated below -18 °C. Upon reconstitution CCL8 should be stored at 4 °C between 2-7 days and for future use below -18 °C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P80075 (UniProt, ExPASy) |
UniProt Secondary AC | A0AV77, P78388 |
UniProt Entry Name | CCL8_HUMAN |
KEGG | hsa:6355 |
String | 9606.ENSP00000378118 |
Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Asp-Ser-Val. |
Biological Activity | The biological activity was determined by measuring the dose dependent mobilization of intracellular calcium (calcium flux) with human THP-1 cells. Significant calcium mobilization is observed with 5ng/mL of recombinant human MCP-2. Human MCP-2 also induces dose dependent chemotaxis of human THP-1 cells with an ED5=3-1 ng/mL corresponding to a Specific Activity of 1,-33,334IU/mg. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |