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Mouse Ptk2 Antibody
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Catalogue No: abx028067
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly (By similarity). Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Research Articles on Mouse Ptk2
| Target | Mouse Ptk2 |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 426-453 amino acids from the Central region of mouse Ptk2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P34152 (UniProt, ExPASy) |
| UniProt Secondary AC | O08578, Q5DTH7, Q8C513, Q8CFH7, Q8CHM2, Q8K2S0, Q9DAW3 |
| UniProt Entry Name | FAK1_MOUSE |
| KEGG | mmu:14083 |
| String | 10090.ENSMUSP00000105663 |
| Molecular Weight | Calculated MW: 119 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |