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Suppressor of IKBKE 1 (Sike1) Antibody
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Catalogue No: abx031456
Price:
US$326.25
(Size: 80 µl)
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Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Research Articles on Suppressor of IKBKE 1 (Sike1)
| Target | Suppressor of IKBKE 1 (Sike1) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9CPR7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8CBP5 |
| UniProt Entry Name | SIKE1_MOUSE |
| String | 10090.ENSMUSP00000029447 |
| Molecular Weight | Calculated MW: 23.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat Sike1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |