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Mouse Syk Antibody
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Catalogue No: abx028629
Price:
US$290.00
(Size: 80 µl)
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Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).
Research Articles on Mouse Syk
| Target | Mouse Syk |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 195-223 amino acids from the Central region of mouse Syk. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48025 (UniProt, ExPASy) |
| UniProt Entry Name | KSYK_MOUSE |
| KEGG | mmu:20963 |
| String | 10090.ENSMUSP00000113852 |
| Molecular Weight | Calculated MW: 71.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Chicken Syk. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |