+44 (0) 1223 755950
+1 832 327 7413
Serine/threonine-Protein Kinase TBK1 (Tbk1) Antibody
REQUEST MORE INFO
Catalogue No: abx029446
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
Research Articles on Serine/threonine-Protein Kinase TBK1 (Tbk1)
| Target | Serine/threonine-Protein Kinase TBK1 (Tbk1) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9WUN2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9CT90, Q9DC03 |
| UniProt Entry Name | TBK1_MOUSE |
| String | 10090.ENSMUSP00000020316 |
| Molecular Weight | Calculated MW: 83.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |