Mitochondrial Ribosomal Protein L1 (MRPL1) Antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.

Target	Mitochondrial Ribosomal Protein L1 (MRPL1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 70-97 amino acids from the N-terminal region of human MRPL1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BYD6 (UniProt, ExPASy)
UniProt Secondary AC	A6NG03, Q4W5B8, Q6IAG4, Q96BW3, Q9H793, Q9NRL5
UniProt Entry Name	RM01_HUMAN
Gene Symbol	MRPL1
String	9606.ENSP00000315017
Molecular Weight	Calculated MW: 36.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow MRPL1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitochondrial Ribosomal Protein L1 (MRPL1)

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