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DNA Mismatch Repair Protein Msh3 (MSH3) Antibody
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Catalogue No: abx004344
Price:
US$203.00
(Size: 20 µl)
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MSH3 Antibody is a Rabbit Polyclonal antibody against MSH3. The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
Research Articles on DNA Mismatch Repair Protein Msh3 (MSH3)
| Target | DNA Mismatch Repair Protein Msh3 (MSH3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 617-761 of human MSH3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20585 (UniProt, ExPASy) |
| UniProt Secondary AC | A1L480, A1L482, A6NMM6, Q6PJT5, Q86UQ6, Q92867 |
| UniProt Entry Name | MSH3_HUMAN |
| Gene Symbol | MSH3 |
| GeneID | 4437 |
| NCBI Accession | NP_004696.2 |
| KEGG | hsa:4437 |
| String | 9606.ENSP00000265081 |
| Molecular Weight | Calculated MW: 127 kDa Observed MW: 127 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |