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Male-Specific Lethal 3 Homolog (Drosophila) (MSL3) Antibody
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Catalogue No: abx029759
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8.
Research Articles on Male-Specific Lethal 3 Homolog (Drosophila) (MSL3)
| Target | Male-Specific Lethal 3 Homolog (Drosophila) (MSL3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human MSL3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8N5Y2 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NCU2, A6NHW8, A8K165, B4DUV8, B7Z227, Q9UG70, Q9Y5Z8 |
| UniProt Entry Name | MS3L1_HUMAN |
| Gene Symbol | MSL3 |
| KEGG | hsa:10943 |
| String | 9606.ENSP00000312244 |
| Molecular Weight | Calculated MW: 59.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse MSL3. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |