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Homeobox Protein MSX-2 (MSX2) Antibody
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Catalogue No: abx031639
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Research Articles on Homeobox Protein MSX-2 (MSX2)
| Target | Homeobox Protein MSX-2 (MSX2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35548 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQN1, Q53XM4, Q9UD60 |
| UniProt Entry Name | MSX2_HUMAN |
| Gene Symbol | MSX2 |
| GeneID | 4488 |
| OMIM | 123101 |
| HGNC | 7392 |
| KEGG | hsa:4488 |
| Ensembl | ENSG00000120149 |
| String | 9606.ENSP00000239243 |
| Molecular Weight | Calculated MW: 28.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |