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Methylthioadenosine Phosphorylase (MTAP) Antibody
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Catalogue No: abx000975
Price:
US$203.00
(Size: 20 µl)
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MTAP Antibody is a Rabbit Polyclonal antibody against MTAP. This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
Research Articles on Methylthioadenosine Phosphorylase (MTAP)
| Target | Methylthioadenosine Phosphorylase (MTAP) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human MTAP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13126 (UniProt, ExPASy) |
| UniProt Entry Name | MTAP_HUMAN |
| Gene Symbol | MTAP |
| GeneID | 4507 |
| NCBI Accession | NP_002442.2 |
| KEGG | hsa:4507 |
| String | 9606.ENSP00000369519 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 29 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |