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Methylenetetrahydrofolate Reductase (MTHFR) Antibody
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Catalogue No: abx031233
Price:
US$290.00
(Size: 80 µl)
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The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Research Articles on Methylenetetrahydrofolate Reductase (MTHFR)
| Target | Methylenetetrahydrofolate Reductase (MTHFR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 266-292 amino acids from the Central region of human MTHFR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42898 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7A6, Q5SNW6, Q5SNW9, Q7Z6M6, Q8IU73, Q9UQR2 |
| UniProt Entry Name | MTHR_HUMAN |
| Gene Symbol | MTHFR |
| KEGG | hsa:4524 |
| String | 9606.ENSP00000365777 |
| Molecular Weight | Calculated MW: 74.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Cow and Monkey MTHFR. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |