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Mitochondrial Translational Initiation Factor 2 (MTIF2) Antibody
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Catalogue No: abx029179
Price:
US$326.25
(Size: 80 µl)
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During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2 (mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2 (mt) shares 32 to 38% amino acid sequence identity with yeast IF-2 (mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Research Articles on Mitochondrial Translational Initiation Factor 2 (MTIF2)
| Target | Mitochondrial Translational Initiation Factor 2 (MTIF2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human MTIF2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P46199 (UniProt, ExPASy) |
| UniProt Secondary AC | D6W5D0 |
| UniProt Entry Name | IF2M_HUMAN |
| KEGG | hsa:4528 |
| String | 9606.ENSP00000263629 |
| Molecular Weight | Calculated MW: 81.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |