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Melatonin Receptor 1A (MTNR1A) Antibody
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Catalogue No: abx034307
Price:
US$290.00
(Size: 80 µl)
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MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Research Articles on Melatonin Receptor 1A (MTNR1A)
| Target | Melatonin Receptor 1A (MTNR1A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 203-229 amino acids from the Central region of human MTNR1A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48039 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AVC5, B0M0L2 |
| UniProt Entry Name | MTR1A_HUMAN |
| KEGG | hsa:4543 |
| String | 9606.ENSP00000302811 |
| Molecular Weight | Calculated MW: 39.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |