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MUC1 (pT1224) Antibody
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Catalogue No: abx032089
Price:
US$326.25
(Size: 80 µl)
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MUC1 is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Research Articles on Mucin 1 (pT1224)
| Target | Mucin 1 (pT1224) |
| Clonality | Polyclonal |
| Target Modification | Thr1224 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC, DB |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/10 - 1/50, DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1224 of human MUC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15941 (UniProt, ExPASy) |
| Molecular Weight | Calculated MW: 122 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |