Mucin 20 (MUC20) Antibody

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Mucin 20 (MUC20)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/2000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human MUC20.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8N307 (UniProt, ExPASy)
UniProt Secondary AC	Q6UX97, Q76I83, Q76I85, Q86ST8, Q8NBY6, Q96KA1, Q9P2I8
UniProt Entry Name	MUC20_HUMAN
Gene Symbol	MUC20
GeneID	200958
OMIM	610360
NCBI Accession	NP_001269435.1
HGNC	23282
KEGG	hsa:200958
Ensembl	ENSG00000176945
String	9606.ENSP00000414350
Molecular Weight	Calculated MW: 72 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mucin 20 (MUC20)

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