Multidrug Resistance Associated Protein 1 (ABCC1) Antibody

Multidrug Resistance Associated Protein 1 (ABCC1) Antibody is a Rabbit Polyclonal antibody for the detection of ABCC1.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

Target	Multidrug Resistance Associated Protein 1 (ABCC1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB 1/500 - 1/1000, IHC 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	ABCC1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P33527 (UniProt, ExPASy)
UniProt Entry Name	MRP1_HUMAN
Gene Symbol	ABCC1
GeneID	4363
OMIM	158343
HGNC	51
KEGG	hsa:4363
Ensembl	ENSG00000103222
String	9606.ENSP00000382342
Molecular Weight	Observed MW: 173 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Multidrug Resistance Associated Protein 1 (ABCC1)

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