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Multidrug Resistance Associated Protein 1 (ABCC1) Antibody
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Catalogue No: abx216930
Price:
US$406.00
(Size: 100 µg)
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Multidrug Resistance Associated Protein 1 (ABCC1) Antibody is a Rabbit Polyclonal antibody for the detection of ABCC1. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
Research Articles on Multidrug Resistance Associated Protein 1 (ABCC1)
| Target | Multidrug Resistance Associated Protein 1 (ABCC1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB 1/500 - 1/1000, IHC 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ABCC1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P33527 (UniProt, ExPASy) |
| UniProt Entry Name | MRP1_HUMAN |
| Gene Symbol | ABCC1 |
| GeneID | 4363 |
| OMIM | 158343 |
| HGNC | 51 |
| KEGG | hsa:4363 |
| Ensembl | ENSG00000103222 |
| String | 9606.ENSP00000382342 |
| Molecular Weight | Observed MW: 173 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |