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Muscle Skeletal Receptor Tyrosine Kinase (MUSK) Antibody
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Catalogue No: abx033588
Price:
US$326.25
(Size: 80 µl)
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MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Research Articles on Muscle Skeletal Receptor Tyrosine Kinase (MUSK)
| Target | Muscle Skeletal Receptor Tyrosine Kinase (MUSK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human MUSK recombinant protein. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15146 (UniProt, ExPASy) |
| UniProt Secondary AC | Q32MJ8, Q32MJ9, Q5VZW7, Q5VZW8 |
| Gene Symbol | MUSK |
| Molecular Weight | Calculated MW: 97.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |