MutY Homolog (MUTYH) Antibody

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Catalogue No: abx001356
Price: US$478.50
(Size: 100 µl)

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Immunofluorescence analysis of U2OS cells using MUTYH Antibody. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1/500 dilution. Blue: DAPI for nuclear staining.
MutY Homolog (MUTYH) Antibody

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Datasheet SDS
MUTYH Antibody is a Rabbit Polyclonal antibody against MUTYH. This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Target MutY Homolog (MUTYH)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications ELISA, IHC, IF/ICC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human MUTYH.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UIF7 (UniProt, ExPASy)
UniProt Secondary AC D3DPZ4, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6
UniProt Entry Name MUTYH_HUMAN
Gene Symbol MUTYH
GeneID 4595
NCBI Accession NP_001041636.1
String 9606.ENSP00000361170
Molecular Weight Calculated MW: 60 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on MutY Homolog (MUTYH)
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