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Major Vault Protein (MVP) Antibody
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Catalogue No: abx025511
Price:
US$623.50
(Size: 100 µl)
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This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. This antibody is supplied as crude ascites.
Research Articles on Major Vault Protein (MVP)
| Target | Major Vault Protein (MVP) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1600. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human MVP. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14764 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96BG4, Q9BPW6, Q9BQT1, Q9UBD1 |
| UniProt Entry Name | MVP_HUMAN |
| KEGG | hsa:9961 |
| String | 9606.ENSP00000378760 |
| Molecular Weight | Calculated MW: 99.3 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow MVP. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |