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Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody
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Catalogue No: abx001476
Price:
US$203.00
(Size: 20 µl)
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MX1 Antibody is a Rabbit Polyclonal antibody against MX1. Mx1 (also known as MxA) is a GTPase that belongs to the Mx family of proteins, which are ubiquitous in eukaryotes and involved in the immune response to viral infections. The human Mx1 is localized in the cytoplasm interfering with the translation of viral proteins, whereas the mouse Mx1 accumulates in the nucleus and inhibits the primary transcription of viral RNA. Mx1 expression is induced by treatment with α/β interferon (INF). This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.
Research Articles on Interferon-Induced GTP-Binding Protein Mx1 (MX1)
| Target | Interferon-Induced GTP-Binding Protein Mx1 (MX1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human MX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20591 (UniProt, ExPASy) |
| UniProt Entry Name | MX1_HUMAN |
| Gene Symbol | MX1 |
| GeneID | 4599 |
| NCBI Accession | NP_001171517.1 |
| KEGG | hsa:4599 |
| String | 9606.ENSP00000381601 |
| Molecular Weight | Calculated MW: 76 kDa Observed MW: 76 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |