Max-Interacting Protein 1 (MXI1) Antibody

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Target	Max-Interacting Protein 1 (MXI1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50539 (UniProt, ExPASy)
UniProt Secondary AC	B1ANN7, D3DR25, D3DRA9, Q15887, Q6FHW2, Q96E53
UniProt Entry Name	MXI1_HUMAN
KEGG	hsa:4601
String	9606.ENSP00000331152
Molecular Weight	Calculated MW: 26.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat MXI1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Max-Interacting Protein 1 (MXI1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue