Max-Interacting Protein 1 (MXI1) Antibody

MXI1 Antibody is a Rabbit Polyclonal antibody against MXI1. Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Target	Max-Interacting Protein 1 (MXI1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50539 (UniProt, ExPASy)
UniProt Secondary AC	B1ANN7, D3DR25, D3DRA9, Q15887, Q6FHW2, Q96E53
UniProt Entry Name	MXI1_HUMAN
Gene Symbol	MXI1
GeneID	4601
NCBI Accession	NP_569157.2
KEGG	hsa:4601
String	9606.ENSP00000331152
Molecular Weight	Calculated MW: 26 kDa Observed MW: 30 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Max-Interacting Protein 1 (MXI1)

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