Max-Interacting Protein 1 (MXI1) Antibody

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Catalogue No: abx005107
Price: US$217.50
(Size: 20 µl)
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Western blot analysis of lysates from Mouse brain, using MXI1 Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 90s.
Max-Interacting Protein 1 (MXI1) Antibody

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Datasheet SDS
MXI1 Antibody is a Rabbit Polyclonal antibody against MXI1. Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Target Max-Interacting Protein 1 (MXI1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P50539 (UniProt, ExPASy)
UniProt Secondary AC B1ANN7, D3DR25, D3DRA9, Q15887, Q6FHW2, Q96E53
UniProt Entry Name MXI1_HUMAN
Gene Symbol MXI1
GeneID 4601
NCBI Accession NP_569157.2
KEGG hsa:4601
String 9606.ENSP00000331152
Molecular Weight Calculated MW: 26 kDa
Observed MW: 30 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Max-Interacting Protein 1 (MXI1)
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