Myosin Binding Protein C, Cardiac (MYBPC3) Antibody

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Catalogue No: abx026810
Price: US$326.25
(Size: 80 µl)
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Myosin Binding Protein C, Cardiac (MYBPC3) Antibody
Myosin Binding Protein C, Cardiac (MYBPC3) Antibody Myosin Binding Protein C, Cardiac (MYBPC3) Antibody

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Datasheet SDS
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Target Myosin Binding Protein C, Cardiac (MYBPC3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/2000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 189-218 amino acids from the N-terminal region of human MYBPC3.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14896 (UniProt, ExPASy)
UniProt Secondary AC A5PL00, Q16410, Q6R2F7, Q9UE27, Q9UM53
UniProt Entry Name MYPC3_HUMAN
KEGG hsa:4607
String 9606.ENSP00000442795
Molecular Weight Calculated MW: 141 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat MYBPC3.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Myosin Binding Protein C, Cardiac (MYBPC3)
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