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MYC (pT58) Antibody
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Catalogue No: abx031945
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
Research Articles on MYC (pT58)
| Target | MYC (pT58) |
| Clonality | Polyclonal |
| Target Modification | Thr58 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, WB, DB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01106 (UniProt, ExPASy) |
| UniProt Secondary AC | A8WFE7, P01107, Q14026 |
| UniProt Entry Name | MYC_HUMAN |
| NCBI Accession | NP_002458.2 |
| KEGG | hsa:4609 |
| String | 9606.ENSP00000479618 |
| Molecular Weight | Calculated MW: 48.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig, Sheep, Zebrafish and Xenopus MYC. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |