Myc Proto-Oncogene Protein (MYC) Antibody

Myc Proto-Oncogene Protein (MYC) Antibody is a mouse monoclonal antibody against Myc Proto-Oncogene Protein (MYC). The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma, in human. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini, in human and mouse. Under conditions of stress, such as high cell densities and methionine deprivation, there is a specific and dramatic increase in the synthesis of the non-AUG initiated protein, suggesting its importance in times of adversity. Alternative splicing results in multiple transcript variants.

Target	Myc Proto-Oncogene Protein (MYC)
Clonality	Monoclonal
Reactivity	Human
Host	Mouse
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Myc Proto-Oncogene Protein (MYC)

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