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N-Myc Proto-Oncogene Protein (MYCN) Antibody
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Catalogue No: abx000732
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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MYCN Antibody is a Rabbit Polyclonal antibody against MYCN. MYCN, also named as BHLHE37 and NMYC, is a transcription factor. It is primarily expressed in normal developing embryos and is thought to be critical in brain and other neural development. It is often amplified in human neuroblastomas. IR34A can suppress MYCN expression, it suggest MYCN has a role in cell growth. The expression of the MCYN is upregulated in a variety of human tumors, most requently neuroblastoma, where the level of expression appearts to increase as teh tumor progress.
Research Articles on N-Myc Proto-Oncogene Protein (MYCN)
| Target | N-Myc Proto-Oncogene Protein (MYCN) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human MYCN |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04198 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53XS5, Q6LDT9 |
| UniProt Entry Name | MYCN_HUMAN |
| Gene Symbol | MYCN |
| GeneID | 4613 |
| NCBI Accession | NP_005369.2 |
| KEGG | hsa:4613 |
| String | 9606.ENSP00000281043 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
