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Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody
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Catalogue No: abx147112
Price:
US$406.00
(Size: 100 µg)
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Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody is a Rabbit Polyclonal antibody for the detection of MYD88. This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Research Articles on Myeloid Differentiation Primary Response Protein MyD88 (MYD88)
| Target | Myeloid Differentiation Primary Response Protein MyD88 (MYD88) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | myeloid differentiation primary response gene |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q99836 (UniProt, ExPASy) |
| UniProt Entry Name | MYD88_HUMAN |
| Gene Symbol | MYD88 |
| GeneID | 4615 |
| OMIM | 602170 |
| HGNC | 7562 |
| KEGG | hsa:4615 |
| Ensembl | ENSG00000172936 |
| String | 9606.ENSP00000401399 |
| Molecular Weight | Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |