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Myeloid Leukemia Factor 1 (MLF1) Antibody
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Catalogue No: abx217001
Price:
US$406.00
(Size: 100 µg)
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Myeloid Leukemia Factor 1 (MLF1) Antibody is a Rabbit Polyclonal antibody for the detection of MLF1. Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Research Articles on Myeloid Leukemia Factor 1 (MLF1)
| Target | Myeloid Leukemia Factor 1 (MLF1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | myeloid leukemia factor 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P58340 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PEU9, Q2TLE3, Q2TLE5, Q8N8F8, Q96MH1 |
| UniProt Entry Name | MLF1_HUMAN |
| Gene Symbol | MLF1 |
| GeneID | 4291 |
| OMIM | 601402 |
| HGNC | 7125 |
| KEGG | hsa:4291 |
| Ensembl | ENSG00000178053 |
| String | 9606.ENSP00000376568 |
| Molecular Weight | Observed MW: 38 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |