Myocyte Enhancer Factor 2C (MEF2C) Antibody

Myocyte Enhancer Factor 2C (MEF2C) Antibody is a Rabbit Polyclonal antibody for the detection of MEF2C.

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes.Controls cardiac morphogenesis and myogenesis,and is also involved in vascular development.Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development,distribution, and electrical activity in the neocortex.Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells.May also be involved in neurogenesis and in the development of cortical architecture (By similarity).Isoform 3 and isoform 4,which lack the repressor domain,are more active than isoform 1 and isoform 2.

Target	Myocyte Enhancer Factor 2C (MEF2C)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	myocyte enhancer factor 2C
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q06413 (UniProt, ExPASy)
UniProt Secondary AC	C9JMZ0, D7F7N5, F8W7V7
UniProt Entry Name	MEF2C_HUMAN
Gene Symbol	MEF2C
GeneID	4208
OMIM	600662
HGNC	6996
KEGG	hsa:4208
Ensembl	ENSG00000081189
String	9606.ENSP00000340874
Molecular Weight	Observed MW: 51 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Myocyte Enhancer Factor 2C (MEF2C)

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