Myocyte-Specific Enhancer Factor 2C (MEF2C) Antibody
REQUEST MORE INFO
Catalogue No: abx011133
Price:
US$420.50
(Size: 100 µg)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
Myocyte-Specific Enhancer Factor 2C (MEF2C) Antibody is a Rabbit Polyclonal antibody for the detection of MEF2C. Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes.Controls cardiac morphogenesis and myogenesis,and is also involved in vascular development.Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development,distribution, and electrical activity in the neocortex.Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells.May also be involved in neurogenesis and in the development of cortical architecture (By similarity).Isoform 3 and isoform 4,which lack the repressor domain,are more active than isoform 1 and isoform 2.
Research Articles on Myocyte-Specific Enhancer Factor 2C (MEF2C)
| Target | Myocyte-Specific Enhancer Factor 2C (MEF2C) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | myocyte enhancer factor 2C |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q06413 (UniProt, ExPASy) |
| UniProt Secondary AC | C9JMZ0, D7F7N5, F8W7V7 |
| UniProt Entry Name | MEF2C_HUMAN |
| Gene Symbol | MEF2C |
| GeneID | 4208 |
| OMIM | 600662 |
| HGNC | 6996 |
| KEGG | hsa:4208 |
| Ensembl | ENSG00000081189 |
| String | 9606.ENSP00000340874 |
| Molecular Weight | Observed MW: 51 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |