+44 (0) 1223 755950
+1 832 327 7413
MyoGEF Antibody
REQUEST MORE INFO
Catalogue No: abx033067
Price:
US$290.00
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It Also activates RHOG and does not activate RAC1, or to a much lower extent than RHOA and RHOG. Its part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, It is required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, it is required for normal macropinocytosis.
Research Articles on MyoGEF
| Target | MyoGEF |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 60-87 amino acids from the N-terminal region of human MyoGEF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q3KR16 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3SWR1, Q8N1P1, Q8WYY1, Q9H8F4, Q9NVK9 |
| UniProt Entry Name | PKHG6_HUMAN |
| KEGG | hsa:55200 |
| String | 9606.ENSP00000380185 |
| Molecular Weight | Calculated MW: 89 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |