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Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody
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Catalogue No: abx216986
Price:
US$406.00
(Size: 100 µg)
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Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody is a Rabbit Polyclonal antibody for the detection of MX1. Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
Research Articles on Interferon-Induced GTP-Binding Protein Mx1 (MX1)
| Target | Interferon-Induced GTP-Binding Protein Mx1 (MX1) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Myxovirus resistance protein 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P20591 (UniProt, ExPASy) |
| UniProt Entry Name | MX1_HUMAN |
| Gene Symbol | MX1 |
| GeneID | 4599 |
| OMIM | 147150 |
| HGNC | 7532 |
| KEGG | hsa:4599 |
| Ensembl | ENSG00000157601 |
| String | 9606.ENSP00000381601 |
| Molecular Weight | Observed MW: 76 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |