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Nicotinamide Phosphoribosyltransferase (NAMPT) Antibody
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Catalogue No: abx034196
Price:
US$326.25
(Size: 80 µl)
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NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Research Articles on Nicotinamide Phosphoribosyltransferase (NAMPT)
| Target | Nicotinamide Phosphoribosyltransferase (NAMPT) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 400-426 amino acids from the Central region of human NAMPT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43490 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D0Q9, A4D0R0, Q3KQV0, Q8WW95 |
| UniProt Entry Name | NAMPT_HUMAN |
| NCBI Accession | NP_005737.1 |
| KEGG | hsa:10135 |
| String | 9606.ENSP00000222553 |
| Molecular Weight | Calculated MW: 55.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Pig NAMPT. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |