Natriuretic Peptide Receptor A Antibody

ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.

Target	Natriuretic Peptide Receptor A
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Natriuretic Peptide Receptor A.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P16066 (UniProt, ExPASy)
UniProt Secondary AC	B0ZBF0, Q5SR08, Q6P4Q3
UniProt Entry Name	ANPRA_HUMAN
NCBI Accession	NP_000897.3
KEGG	hsa:4881
String	9606.ENSP00000357669
Molecular Weight	Calculated MW: 119 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Natriuretic Peptide Receptor A

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