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Natriuretic Peptides B (NPPB) Antibody
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Catalogue No: abx001791
Price:
US$203.00
(Size: 20 µl)
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NPPB Antibody is a Rabbit Polyclonal antibody against NPPB. This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
Research Articles on Natriuretic Peptides B (NPPB)
| Target | Natriuretic Peptides B (NPPB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 35-134 of human BNP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16860 (UniProt, ExPASy) |
| UniProt Secondary AC | B0ZBE9, Q6FGY0, Q9P2Q7 |
| UniProt Entry Name | ANFB_HUMAN |
| Gene Symbol | NPPB |
| GeneID | 4879 |
| OMIM | 600295 |
| NCBI Accession | NP_002512.1 |
| HGNC | 7940 |
| KEGG | hsa:4879 |
| Ensembl | ENSG00000120937 |
| String | 9606.ENSP00000365651 |
| Molecular Weight | Calculated MW: 15 kDa Observed MW: 14 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1.56 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |