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N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP) Antibody
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Catalogue No: abx217223
Price:
US$406.00
(Size: 100 µg)
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N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP) Antibody is a Rabbit Polyclonal antibody for the detection of NPPB. NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.
Research Articles on N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP)
| Target | N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | natriuretic peptide precursor B |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P16860 (UniProt, ExPASy) |
| UniProt Secondary AC | B0ZBE9, Q6FGY0, Q9P2Q7 |
| UniProt Entry Name | ANFB_HUMAN |
| OMIM | 600295 |
| KEGG | hsa:4879 |
| String | 9606.ENSP00000365651 |
| Molecular Weight | Observed MW: 15 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |