Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody

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Catalogue No: abx216441
Price: US$406.00
(Size: 100 µg)

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Datasheet SDS
Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody is a Rabbit Polyclonal antibody for the detection of NCR1.

The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Target Natural Cytotoxicity Triggering Receptor 1 (NCR1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Natural cytotoxicity triggering receptor 1
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC O76036 (UniProt, ExPASy)
UniProt Entry Name NCTR1_HUMAN
Gene Symbol NCR1
GeneID 9437
OMIM 604530
HGNC 6731
KEGG hsa:9437
Ensembl ENSG00000189430
String 9606.ENSP00000291890
Molecular Weight Observed MW: 46 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Natural Cytotoxicity Triggering Receptor 1 (NCR1)