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Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
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Catalogue No: abx216441
Price:
US$406.00
(Size: 100 µg)
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Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody is a Rabbit Polyclonal antibody for the detection of NCR1. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
Research Articles on Natural Cytotoxicity Triggering Receptor 1 (NCR1)
| Target | Natural Cytotoxicity Triggering Receptor 1 (NCR1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Natural cytotoxicity triggering receptor 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O76036 (UniProt, ExPASy) |
| UniProt Entry Name | NCTR1_HUMAN |
| Gene Symbol | NCR1 |
| GeneID | 9437 |
| OMIM | 604530 |
| HGNC | 6731 |
| KEGG | hsa:9437 |
| Ensembl | ENSG00000189430 |
| String | 9606.ENSP00000291890 |
| Molecular Weight | Observed MW: 46 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |