Nibrin (NBN) Antibody

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Catalogue No: abx026436
Price: US$326.25
(Size: 80 µl)

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Nibrin (NBN) Antibody
Nibrin (NBN) Antibody Nibrin (NBN) Antibody Nibrin (NBN) Antibody

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Datasheet SDS
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Target Nibrin (NBN)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60934 (UniProt, ExPASy)
UniProt Secondary AC B2R626, B2RNC5, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2
UniProt Entry Name NBN_HUMAN
Gene Symbol NBN
KEGG hsa:4683
String 9606.ENSP00000265433
Molecular Weight Calculated MW: 85 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Nibrin (NBN)
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