Neural Cell Adhesion Molecule 1 / CD56 (NCAM1) Antibody

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Catalogue No: abx000705
Price: US$217.50
(Size: 20 µl)
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Western blot analysis of lysates from mouse brain, using NCAM1 / CD56 Antibody. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Neural Cell Adhesion Molecule 1 / CD56 (NCAM1) Antibody Neural Cell Adhesion Molecule 1 / CD56 (NCAM1) Antibody Neural Cell Adhesion Molecule 1 / CD56 (NCAM1) Antibody

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Datasheet SDS
NCAM1 Antibody is a Rabbit Polyclonal antibody against NCAM1. Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurones, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronectin-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described.

Target Neural Cell Adhesion Molecule 1 / CD56 (NCAM1)
Clonality Polyclonal
Reactivity Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 759-858 of human NCAM1 / CD56.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P13591 (UniProt, ExPASy)
Gene Symbol NCAM1
GeneID 4684
NCBI Accession NP_851996.2
Molecular Weight Calculated MW: 95 kDa
Observed MW: 120/140/180 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Neural Cell Adhesion Molecule 1 / CD56 (NCAM1)
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