Nuclear Receptor Coactivator 3 (NCOA3) Antibody

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Target	Nuclear Receptor Coactivator 3 (NCOA3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 344-372 amino acids from the N-terminal region of human NCOA3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y6Q9 (UniProt, ExPASy)
UniProt Entry Name	NCOA3_HUMAN
Gene Symbol	NCOA3
String	9606.ENSP00000361066
Molecular Weight	Calculated MW: 155 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat NCOA3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nuclear Receptor Coactivator 3 (NCOA3)

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